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Bioethical aspects of basic research and medical applications of human stem cells Biol. Res.
Santos,Manuel J; Ventura-Juncá,Patricio.
The new discoveries, the extraordinary dynamism in human stem cell (SC) research, and the great expectations of the benefits in clinical treatment of many diseases are on the edge of unparalleled advances in both: 1) the understanding of basic mechanisms of cell differentiation and development and 2) the translation from basic research to new clinical therapies. Human stem cells are obtained from different sources, such as embryo, fetal, and adult tissues, in vitro induction (iPS cells) or transdifferentiation. The evidence that these cells are pluripotent (or multipotent), meaning they have the ability to differentiate into all body tissues or tissues of the same lineage, raises the possibility that they could regenerate diseased or damaged tissue in...
Tipo: Journal article Palavras-chave: Human Stem cells; Basic research; Bioethics; Clinical trials; Translational research.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300013
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Pecuniary, Non-Pecuniary, and Downstream Research Spillovers: The Case of Canola AgEcon
Gray, Richard S.; Malla, Stavroula; Tran, Kien C..
This paper develops an empirical framework for estimating a number of inter-firm and downstream research spillovers in the canola crop research industry. The spillovers include basic research, human capital/ knowledge (as measured through other-firm expenditures), and genetics (as measured through yields of other-firms). The model used to examine spillover effects on research productivity provides evidence that there are many positive inter-firm non-pecuniary research spillovers, which is consistent with a research clustering effect. The second model, which examines spillovers at the level of firm revenue , shows that, while private firms tend to crowd one another, public firm expenditure on basic and applied research creates a crowding-in effect for...
Tipo: Conference Paper or Presentation Palavras-chave: Basic research; Applied research; Public research expenditures; Private research expenditures; Biotechnology; Research and Development/Tech Change/Emerging Technologies; O3.
Ano: 2005 URL: http://purl.umn.edu/24776
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PUBLIC BASIC RESEARCH AND DIFFUSION OF RESEARCH BENEFITS AgEcon
Malla, Stavroula; Gray, Richard S..
The paper examine the economic impact of pricing and access to basic research IP. The analysis uses a Sallop circle model of a monopolistically competitive industry to examine the applied research output and firm entry. Under plausible conditions basic research IP spillovers will create rents for the applied research sector, which are dissipated through socially excess firm entry. Charging a price or restricting access to basic research IP could enhance social welfare.
Tipo: Conference Paper or Presentation Palavras-chave: Pricing; Intellectual property; Downstream effects; Basic research; Monopolistic competition; Rent dissipation; Toll goods; Research and Development/Tech Change/Emerging Technologies.
Ano: 2007 URL: http://purl.umn.edu/9877
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